Claro Scientific, LLC
Claro Scientific, LLC

SpectraWave™

What is SpectraWave?

SpectraWave is a proprietary set of interpretation models and optical properties databases used for analysis, quantification and characterization of complex micron and sub-micron particles, and particle-particle interactions. For Claro, a particle can be defined as but not limited to cells, bacteria, proteins, and chemical compounds.

How does SpectraWave Work?

Claro’s technology is founded on the principles of spectroscopy. Spectroscopy is the study of the interaction between matter and radiated energy. Light interacts with matter in a variety of different ways such as absorption, reflection, refraction, angular scattering, transmission, fluorescence, and polarization. Theses interactions can be captured using spectrometers. The basic function of a spectrometer is to take in light, break it into its spectral components(i.e. wavelengths), digitize the signal as a function of wavelength, display it through a computer, and store the data as a file.

SpectraWave Signal Collection

The data files generated by spectrometers contain a wealth of information about a sample of interest. The difficulty is in extracting the information from the spectroscopic data and understanding how it relates to a given sample. By using the powerful analysis capabilities of SpectraWave, these data files are transformed into quantifiable information about a sample’s characteristics in minutes.

SpectraWave

 

What sort of sample characteristics can be determined with SpectraWave?

The ability to characterize a sample of interest depends on a number of parameters

  1. The type of measurement performed (reflectance, transmission, fluorescence, etc.)
  2. The electromagnetic portion of the spectrum where the measurement is taking place (uv, vis, nir, etc.)
  3. Robustness of the interpretation models used for analysis

 

Below is a list of characterization parameters as they relate to the types of measurements performed.

Spectroscopic Method Sample Characteristics
Transmission/Absorption Size and size distribution, shape, chemical composition, particle count
Angular Scattering Size and size distribution, shape, structure, particle count
Forward Scattering Size, shape, orientation
Fluorescence Chemical composition, conformation, internal structure, fluorophore interactions
Polarization Size, shape, internal structure
Reflectance Size, chemical composition, particle count
Raman Chemical composition

 

Can SpectraWave resolve more than one population?

Absolutely, SpectraWave quantitatively resolves multiple populations from a single measurement.

 

What size ranges is SpectraWave capable of resolving?

SpectraWave is capable or resolving sizes as small as 10nm to as large as 20μm.

 

Is SpectraWave capable or resolving more than one measurement type at a time?

Yes, Multiple measurement modes can be resolved simultaneously.