Claro Scientific, LLC
Claro Scientific, LLC

Academic Publications

Selected References

Huffman D, Serebrennikova Y, Smith JM, Lindon J, Garcia-Rubio L. 2013. Detection of particulate contaminants and protein aggregates in protein solution using multiwavelength transmission spectroscopy (MWT). Trends in Applied Spectroscopy 10, 73 – 8

Smith, JM, Roth A., Huffman D, Serebrennikova Y, Lindon J, and Garcia-Rubio L.  2012. Multiwavelength transmission spectroscopy revisited for micron and submicron particle characterization. Applied Spectroscopy 66, 1186-1196

Alupoaei, C. E. and García-Rubio, L. H., 2004. Growth behavior of microorganisms using UV-Vis spectroscopy: Escherichia coli. Biotechnology and Bioengineering 86, 163-167.

Alupoaei, C. E. and García-Rubio, L. H., 2005. An interpretation model for the UV-Vis spectra of microorganisms. Chemical Engineering Communications 192, 198-218.

Alupoaei, C. E., Olivares, J. A., and García-Rubio, L. H., 2004. Quantitative spectroscopy analysis of prokaryotic cells: vegetative cells and spores. Biosensors & Bioelectronics 19, 893-903.

Callahan, M. R., Rose, J. B., and García-Rubio, L., 2003. Use of multiwavelength transmission spectroscopy for the characterization of Cryptosporidium parvum oocysts: Quantitative interpretation. Environmental Science & Technology 37, 5254-5261.

García-Lopez, A. C. and García-Rubio, L. H., 2008. Rayleigh-Debye-Gans as a model for continuous monitoring of biological particles: Part II, development of a hybrid model. Optics Express 16, 4671-4687.

García-Lopez, A. C., Snider, A. D., and García-Rubio, L. H., 2006. Rayleigh-Debye-Gans as a model for continuous monitoring of biological particles: Part I, assessment of theoretical limits and approximations. Optics Express 14, 8849-8865.

García-Rubio, L. H., 1982. The effect of composition, sequence length, and tacticity on the UV absorption analysis of styrene copolymers in solution. Journal of Applied Polymer Science 27, 2043-2052.

García-Rubio, L. H., 1987a. The effect of molecular size on the absorption spectra of macromolecules. Macromolecules 20, 3070-3075.

García-Rubio, L. H., 1987b. Multiple detectors in size exclusion chromatography – Signal analysis. In: Provder, T. (Ed.), Detection and Data Analysis in Size Exclusion Chromatography. American Chemical Society, Washington, D.C.

García-Rubio, L. H., 1989. Characterization of proteins during aggregation using turbidimetry. Chemical Engineering Communications 80, 193-210.

García-Rubio, L. H., 1992. Refractive index effects on the absorption spectra of macromolecules. Macromolecules 25, 2608-2613.

García-Rubio, L. H., Lopez-Menacho, C. A., and Grossman, S., 1993. Characterization of proteins during aggregation: 2. Use of model molecules for spectroscopy analysis. Chemical Engineering Communications 122, 85-101.

García-Rubio, L. H., Ro, N., and Patel, R. D., 1984. UV analysis of benzoyl peroxide initiated styrene polymerizations and copolymerizations. Macromolecules 17, 1998-2005.

Grossman, S. H., Akinade, F. A., and García-Rubio, L., 1990. A physicochemical comparison of the isozymes of creatine kinase from rabbit brain and muscle. Biochimica Et Biophysica Acta 1040, 311-316.

Huffman, D. E., Serebrennikova, Y. M., Smith, J. M., Leparc, G. F., and García-Rubio, L. H., 2009. New method for the detection of microorganisms in blood:  Application of quantitative interpretation model to aerobic blood cultures. Journal of Biomedical Optics 14, Article No. 034043.

Marquez, E., Bhethanabotla, V. R., and García-Rubio, L. H., 1993. Conformation effects on the absorption spectra of macromolecules. Macromolecules 26, 479-484.

Mattley, Y., Leparc, G., Potter, R., and García-Rubio, L., 2000. Light scattering and absorption model for the quantitative interpretation of human blood platelet spectral data. Photochemistry and Photobiology 71, 610-619.

Mattley, Y., Orton, S., Leparc, G., Potter, R., and García-Rubio, L., 1996. UV/vis spectroscopic measurements as indicators of platelet quality. Biochemistry 35, 62-62.

Narayanan, S., Galloway, L., Nonoyama, A., Leparc, G. F., García-Rubio, L. H., and Potter, R. L., 2002. UV-visible spectrophotometric approach to blood typing II: phenotyping of subtype A(2) and weak D and whole blood analysis. Transfusion 42, 619-626.

Narayanan, S., Leparc, G. F., García-Rubio, L. H., and Potter, R. L., 1999a. A UV/visible spectroscopic approach to blood typing: Analysis of antibody induced erythrocyte aggregation. Faseb Journal 13, A1455-A1455.

Narayanan, S., Orton, S., Leparc, G. F., García-Rubio, L. H., and Potter, R. L., 1999b. Ultraviolet and visible light spectrophotometric approach to blood typing: objective analysis by agglutination index. Transfusion 39, 1051-1059.

Narayanan, S., Potter, R. L., and García-Rubio, L. H., 1996. Use of multi-wavelength UV/visible spectroscopy to monitor protein structure. Biochemistry 35, 24-24.

Serebrennikova, Y. M., Patel, J., Milhous, W., and Garcia-Rubio, L. H., 2010a. Quantitative analysis of morphological alterations in Plasmodium falciparum infected red blood cells through theoretical interpretation of spectral measurements. Journal of Theoretical Biology 265, 493–500.

Serebrennikova, Y. M., Patel, Y. M., and García-Rubio, L. H., 2010b. Interpretation of the UV-visible spectra of malaria parasite Plasmodium falciparum. Applied Optics 49, 180-188.

Serebrennikova, Y. M., Smith, J. M., Huffman, D. E., Leparc, G. F., and García-Rubio, L. H., 2008. Quantitative interpretations of Visible-NIR reflectance spectra of blood. Optics Express 16, 18215-18229.

Smith, J. M., Serebrennikova, Y. M., Huffman, D. E., Leparc, G. F., and García-Rubio, L. H., 2008. A new method for the detection of microorganisms in blood cultures: Part I. Theoretical analysis and simulation of blood culture processes. Canadian Journal of Chemical Engineering 86, 947-959.

Spear, A. H., Daly, K., Huffman, D., and García-Rubio, L., 2009. Progress in developing a new detection method for the harmful algal bloom species, Karenia brevis, through multiwavelength spectroscopy. Harmful Algae 8, 189-195.